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Taubenberger, that during the period of the pandemic, the virus didn’t undergo a dramatic switch that could describe the unusually high mortality it eventually caused. In today’s study, the autopsy components demonstrated that the virus replicated not merely in the top respiratory system but also the low respiratory system, in a pattern nearly the same as that of this year’s 2009 pandemic influenza virus. The team found evidence that two virus variants were circulating in 1918 also. In one, an integral viral protein known as hemagglutinin bound well to receptors on human being respiratory cells, as the hemagglutinin from the additional variant bound less effectively.