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This can be a limitation in capturing CTCs from particular tumor types, notably triple-negative breast cancers, Atwal said. Captured CTCs were amenable to biomarker analyses such as HER2 position, qRT-PCR for breast malignancy subtype markers, KRAS mutation detection and EGFR staining by immunofluorescence, the experts found. In individuals with HER2-positive breasts cancer, HER2 position in CTCs and tumor tissue generally correlated; however, in a single patient subset, HER2 status changed from the principal tumor at diagnosis.This content was reprinted from kaiserhealthnews.org with permission from the Henry J. Kaiser Family members Foundation. Kaiser Health Information, an independent news service editorially, is a scheduled plan of the Kaiser Family Foundation, a nonpartisan healthcare policy research company unaffiliated with Kaiser Permanente. Trials entered on the Register will range between those researching new medicines and treatments to brand-new and/or improved surgical treatments and medical products. The Australian Government is usually spending $1.5 million through the National Health insurance and Medical Study Council to determine the Register. Professor John Simes from the Clinical Trials Center in Sydney will continue to work with the NHMRC to begin with developing this nationwide register in the arriving months.